Table I. Characteristics of the Study Population, Comparing Survivor Participants and Non-Participants.
Participants (n = 319) |
Non-participantsa (n = 388) |
|||||
---|---|---|---|---|---|---|
n | %c | n | %c | P-Valueb | ||
Sex | ||||||
Male | 140 | 44 | 223 | 58 | 0.001 | |
Female | 179 | 56 | 165 | 42 | ||
Language region | ||||||
German | 238 | 75 | 290 | 75 | 0.967 | |
French/Italian | 81 | 25 | 98 | 25 | ||
Migration background | ||||||
None (Swiss) | 293 | 92 | 349 | 90 | 0.422 | |
Other countries | 25 | 8 | 37 | 10 | ||
Education | ||||||
Primary | 33 | 10 | 48 | 12 | 0.105 | |
Secondary | 93 | 29 | 131 | 34 | ||
Tertiary | 59 | 19 | 48 | 13 | ||
Unknown | 134 | 42 | 161 | 41 | ||
Diagnosis (ICCC-3) | ||||||
I Leukemia | 115 | 36 | 121 | 31 | 0.648 | |
II Lymphoma | 59 | 18 | 81 | 21 | ||
III CNS tumor | 38 | 11 | 62 | 16 | ||
IV Neuroblastoma | 8 | 4 | 12 | 5 | ||
V Retinoblastoma | 5 | 2 | 9 | 2 | ||
VI Renal tumor | 21 | 6 | 19 | 5 | ||
VII Hepatic tumor | 1 | 1 | 2 | 1 | ||
VIII Bone tumor | 22 | 7 | 23 | 6 | ||
IX Soft tissue sarcoma | 20 | 6 | 18 | 5 | ||
X Germ cell tumor | 9 | 3 | 17 | 3 | ||
XI and XII Other tumord | 8 | 2 | 5 | 1 | ||
Langerhans cell histiocytosis | 13 | 4 | 19 | 4 | ||
Surgery | ||||||
No | 95 | 30 | 99 | 26 | 0.206 | |
Yes | 224 | 70 | 289 | 74 | ||
Chemotherapy | ||||||
No | 47 | 15 | 82 | 21 | 0.043 | |
Yes | 272 | 85 | 306 | 79 | ||
Radiotherapy | ||||||
No radiotherapy | 195 | 61 | 260 | 67 | 0.741 | |
Body and limbs radiation | 76 | 24 | 65 | 17 | ||
Cranio-spinal radiation | 48 | 15 | 63 | 16 | ||
Bone marrow transplantation | ||||||
No | 302 | 95 | 363 | 94 | 0.533 | |
Yes | 17 | 5 | 25 | 6 | ||
Relapse | ||||||
No | 281 | 88 | 354 | 91 | 0.168 | |
Yes | 38 | 12 | 34 | 9 | ||
Reported late-effects | ||||||
No | 185 | 59 | 249 | 67 | 0.026 | |
Yes | 130 | 41 | 123 | 33 | ||
Treating clinic | ||||||
University clinic | 239 | 75 | 290 | 75 | 0.956 | |
Cranio-spinal radiation | 80 | 25 | 98 | 25 | ||
Participants (n = 319) |
Non-participantsa (n = 388) |
|||||
Mean | SD | Mean | SD | P-Valuee | ||
Age at study | 21.3 | 4.1 | 21.7 | 3.8 | 0.852 | |
Age at diagnosis | 8.9 | 4.7 | 8.9 | 4.5 | 0.512 | |
Time since diagnosis | 12.5 | 3.8 | 12.8 | 3.6 | 0.857 |
Note Percentages are based upon available data for each variable. CNS, Central Nervous System; ICCC-3, International Classification of Childhood Cancer—Third Edition.
Non-participants include: 375 survivors who did not respond, 13 who refused to participate (Supplemental Figure 1)
P-Value calculated from Chi-square statistics comparing survivor participants and survivor non-participants
Column percentages are given
Other malignant epithelial neoplasms, malignant melanomas and other or unspecified malignant neoplasms
P-Value calculated on two-sample mean-comparison test (t-test).