Figure 4.
Microvesicles from pancreatic cancer patients increase the migration and proliferation of PANC-1 cells. PANC-1 cells were exposed to microvesicles isolated from patients with pancreatic cancer or healthy control for 24 h before the migration and proliferation assay. We used pooled microvesicles in this assay due to limited amount of serum from each patient. (a) CMTCs migrated faster than HMTCs or PANC-1 cells without exposure. Error bars represent SD (n = 3). (b) CMTCs have higher proliferation activity. (c) Compared with HMTCs, CMTCs were more resistant to treatment with gemcitabine.
