Table 1.
Characteristics of participants.
| Included participants (n = 3612) | Excluded participants* (n = 10,929) | ||||
|---|---|---|---|---|---|
|
|
|
|
|||
| N with available data | Mean (SD)/Median (IQR)/Percentage (%) | N with available data | Mean (SD)/Median (IQR)/Percentage (%) | P for difference | |
| Latent psychosocial adversity scores | |||||
| Sexual abuse score (SD scores) | 3378 | 0.17 (0.54) | – | – | – |
| Non-sexual abuse score (SD scores) | |||||
| Parental mental illness score (SD scores) | 3612 | 0.16 (0.54) | – | – | – |
| Household dysfunction score (SD scores) | 3613 | 0.10 (0.78) | – | – | – |
| Maternal lack of care score (SD scores) | 3550 | 0.08 (0.83) | – | – | – |
| Maternal overprotection score (SD scores) | 3549 | < 0.012 (0.78) | – | – | – |
| Cumulative psychosocial adversity score (SD scores) | 3612 | 0.14 (0.77) | – | – | – |
| Outcomes | |||||
| BMI (kg/m2) | 3612 | 26.49 (5.23) | 1084 | 27.24 (5.81) | < 0.01 |
| Waist circumference (cm) | 3610 | 84.27 (13.31) | 1085 | 86.01 (12.16) | < 0.01 |
| Systolic blood pressure (mm/Hg) | 3558 | 118.33 (12.49) | 1076 | 118.17 (12.57) | 0.72 |
| Diastolic blood pressure (mm/Hg) | 3558 | 72.52 (10.18) | 1076 | 72.81 (11.16) | 0.43 |
| Glucose (mmol/dl) | 3219 | 5.27 (0.89) | 888 | 5.37 (1.24) | < 0.01 |
| Insulin (u/ml)* | 3202 | 4.58 (3.21, 6.7) | 888 | 4.91 (3.42, 7.53) | < 0.01 |
| Triglycerides (mmol/l)* | 3218 | 0.88 (0.67, 1.18) | 888 | 0.90 (0.69, 1.23) | 0.05 |
| LDL cholesterol (mmol/l) | 3218 | 2.99 (0.80) | 888 | 2.96 (0.83) | 0.48 |
| HDL cholesterol (mmol/l) | 3218 | 1.49 (0.39) | 888 | 1.44 (0.38) | < 0.01 |
| CRP (mmol/l)* | 3217 | 2.10 (3.59) | 888 | 2.68 (4.46) | < 0.01 |
| cIMT (mm) | 3493 | 0.56 (0.06) | 1050 | 0.55 (0.06) | 0.09 |
| Arterial distensibility (mm) | 3485 | 0.50 (0.12) | 1049 | 0.50 (0.12) | 0.73 |
| Covariables | |||||
| Age at outcome assessment | 3612 | 48.13 (4.35) | 1105 | 47.12 (4.82) | < 0.01 |
| Smoking during adulthood | |||||
| Current smoker | 3612 | 10.4 | 9302 | 23.3 | < 0.01 |
| Ex-smoker | 9.4 | 15.5 | |||
| Never smoked | 80.2 | 61.3 | |||
| Ethnicity | |||||
| White | 3612 | 98.2 | 8636 | 97.1 | < 0.01 |
| Non-white | 1.8 | 2.9 | |||
| Father’s (childhood) SEP | |||||
| Non-manual | 3612 | 55.5 | 5890 | 42.7 | < 0.01 |
| Manual | 46.5 | 57.3 | |||
| Adulthood SEP | |||||
| High | 3612 | 66.2 | 7808 | 49.9 | < 0.01 |
| Low | 33.8 | 50.1 | |||
SD – standard deviation. IQR – interquartile range. BMI – body mass index. LDL- low density lipoprotein. HDL – high density lipoprotein. CRP – C-reactive protein. cIMT – carotid intima-media thickness.
*
Median and interquartile range are presented for non-normally distributed variables.
Distributions of latent psychosocial adversity scores are not given for excluded participants because they were only modelled those participants eligible to be included in the analysis. Psychosocial exposures, ethnicity and childhood and adulthood SEP are given as percentages.