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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2017 Nov 22;338:112–123. doi: 10.1016/j.taap.2017.11.014

Figure 9. Effects of PPARα activation and deficiency on mRNA expression of BA and cholesterol transporters in the ileum.

Figure 9

(A) Heat map of genes involved in BA and cholesterol transport in the ileum. The colors on the heatmap corresponded to the relative changes in average gene expression. Red represents up-regulation while green represents down-regulation. (2) QuantiGene Plex 2.0 Assay was performed to measure the gene expression of BA transporters (Asbt, Ibabp, Ostα, and Ostβ) and cholesterol transporters (Npc1l1, Abca1, Abcg5, and Abcg8). Relative mRNA levels were calculated with vehicle controls set as 100%. Data represent means ± S.E.M. *p<0.05 versus vehicle treatment group; #p<0.05 versus WT group.

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