Table 2. Manual analysis of differentially expressed immune related genes across time points for NV+ and NV− flies list of Drosophila genes with potential relevance to the immune response [21], FlyBase [20], The Interactive Fly list of RNAi genes [22]. Some genes are represented at more than one time point. The numbers in the column indicate the total number of genes found either upregulated or downregulated for each group.
Category name | Day 2 |
Day 10 |
Day 20 |
Day 30 |
||||
Up 47 | Down 0 | Up 112 | Down 0 | Up 86 | Down 2 | Up 130 | Down 26 | |
Microbial recognition and phagocytosis | 9 | 0 | 27 | 0 | 22 | 1 | 28 | 2 |
Toll and IMD pathway signaling | 4 | 0 | 14 | 0 | 10 | 0 | 29 | 0 |
Other signaling | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 1 |
Melanization | 1 | 0 | 4 | 0 | 3 | 0 | 2 | 1 |
Coagulation | 5 | 0 | 6 | 0 | 6 | 0 | 7 | 0 |
Hematopoiesis and cellular response | 2 | 0 | 4 | 0 | 4 | 0 | 4 | 1 |
Antimicrobial peptides | 4 | 0 | 14 | 2 | 6 | 0 | 10 | 4 |
Antiviral defense | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 15 |
Stress response | 2 | 0 | 5 | 0 | 4 | 0 | 8 | 2 |
Induced molecules | 19 | 0 | 36 | 0 | 29 | 0 | 38 | 0 |