TABLE 1.
Results from analysis of systolic heart failure data
| Variable | Cox regression | VIMP | Marginal VIMP | |||
|---|---|---|---|---|---|---|
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| β̂ | P value | β̂inbag | Δβ | Errstep |
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| Peak VO2 | −0.06 | .002 | −0.06 | 1.94 | 32.40 | 0.25 |
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| BUN | 0.02 | .000 | 0.02 | 1.67 | 30.81 | 0.37 |
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| Exercise time | 0.00 | .008 | 0.00 | 1.37 | 30.80 | 0.08 |
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| Male | 0.47 | .000 | 0.47 | 0.52 | 30.01 | 0.37 |
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| beta-blocker | −0.23 | .006 | −0.23 | 0.30 | 29.34 | 0.16 |
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| Digoxin | 0.36 | .000 | 0.36 | 0.30 | 29.00 | 0.22 |
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| Serum sodium | −0.02 | .071 | −0.02 | 0.20 | 28.93 | 0.07 |
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| Age | 0.01 | .022 | 0.01 | 0.18 | 28.99 | −0.03 |
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| Resting heart rate | 0.01 | .058 | 0.01 | 0.14 | 28.93 | 0.04 |
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| Angiotensin receptor blocker | 0.26 | .067 | 0.27 | 0.13 | 28.92 | 0.02 |
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| LVEF | −0.01 | .079 | −0.01 | 0.11 | 28.86 | 0.03 |
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| Aspirin | −0.21 | .018 | −0.21 | 0.11 | 28.83 | 0.03 |
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| Resting systolic blood pressure | 0.00 | .158 | 0.00 | 0.07 | 28.83 | 0.00 |
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| Diabetes insulin treated | 0.26 | .057 | 0.25 | 0.07 | 28.87 | −0.02 |
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| Previous CABG | 0.11 | .316 | 0.12 | 0.07 | 28.86 | −0.02 |
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| Coronary artery disease | 0.12 | .284 | 0.12 | 0.06 | 28.92 | −0.04 |
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| Body mass index | 0.00 | .800 | 0.00 | 0.00 | 28.96 | −0.05 |
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| Potassium-sparing diuretics | −0.14 | .134 | −0.14 | −0.03 | 28.97 | −0.01 |
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| Previous MI | 0.29 | .012 | 0.30 | −0.03 | 29.02 | −0.01 |
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| Thiazide diuretics | 0.04 | .707 | 0.04 | −0.04 | 29.07 | −0.05 |
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| Peak respiratory exchange ratio | 0.12 | .701 | 0.12 | −0.04 | 29.12 | −0.05 |
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| Statin | −0.12 | .183 | −0.13 | −0.04 | 29.19 | −0.07 |
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| Antiarrhythmic | 0.04 | .700 | 0.04 | −0.04 | 29.25 | −0.06 |
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| Diabetes, noninsulin-treated | 0.01 | .930 | 0.00 | −0.05 | 29.30 | −0.06 |
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| Dihydropyridine | 0.03 | .851 | 0.03 | −0.05 | 29.35 | −0.05 |
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| Serum glucose | 0.00 | .486 | 0.00 | −0.05 | 29.42 | −0.07 |
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| Previous PCI | −0.06 | .557 | −0.06 | −0.05 | 29.48 | −0.05 |
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| ICD | 0.04 | .676 | 0.03 | −0.05 | 29.55 | −0.07 |
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| Anticoagulation | −0.01 | .933 | −0.01 | −0.06 | 29.61 | −0.06 |
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| Pacemaker | −0.02 | .851 | −0.01 | −0.06 | 29.67 | −0.06 |
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| Current smoker | 0.03 | .807 | 0.03 | −0.06 | 29.74 | −0.06 |
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| Nitrates | −0.04 | .623 | −0.04 | −0.06 | 29.80 | −0.06 |
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| Serum hemoglobin | 0.00 | .923 | 0.01 | −0.06 | 29.87 | −0.07 |
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| Black | 0.07 | .589 | 0.06 | −0.07 | 29.95 | −0.08 |
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| Nondihydropyridine | −0.30 | .510 | −0.51 | −0.07 | 30.03 | −0.08 |
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| Loop diuretics | −0.07 | .541 | −0.08 | −0.07 | 30.09 | −0.06 |
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| ACE inhibitor | 0.10 | .371 | 0.11 | −0.09 | 30.15 | −0.06 |
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| Vasodilators | −0.08 | .606 | −0.07 | −0.09 | 30.25 | −0.09 |
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| Creatinine clearance | 0.00 | .624 | 0.00 | −0.11 | 30.31 | −0.06 |
VIMP, Variable importance; VO2, oxygen consumption; BUN, blood urea nitrogen; LVEF, left ventricular ejection fraction; CABG, coronary artery bypass grafting; MI, myocardial infarction; PCI, percutaneous coronary intervention; ICD, implantable cardioverter defibrillators; ACE, angiotensin-converting enzyme.