Table 1.
Pearson’s correlation coefficients show the degree of orthogonality between HPLC (columns) and DMS separations (rows).
| RP | MM-RP | MM-HILIC | Amide | pHILIC™ | cHILIC™ | NH2 | |
|---|---|---|---|---|---|---|---|
|
| |||||||
| Positive mode | 0.527** | 0.520** | 0.146* | −0.175* | −0.017 | −0.213** | 0.052 |
|
| |||||||
| Negative mode | 0.436** | 0.343** | 0.162* | 0.073 | 0.041 | 0.002 | 0.06 |
|
|
|||||||
Data are presented for protonated (positive mode) and deprotonated adducts (negative mode) in DMS. HPLC columns (see [11]): RP, reversed phase. MM-RP, mixed-mode reversed phase. MM-HILIC, mixed-mode hydrophilic interaction liquid chromatography. pHILIC/cHILIC, zwitterionic HILIC. NH2, amine.
*
significant at 0.05 level.
**
significant at 0.01 level