Fig. 4.

Non-additive associations for FUT2. Association results under additive and non-additive logistic regression models for predicted FUT2 heterozygous or homozygous knockouts (KOs) with a difference between non-additive model AIC and additive model AIC < −1. The left panel shows the number of cases per phenotype. The middle-left panel shows the -log₁₀ p value for the KO association analysis. The middle-right panel shows the estimated log odds ratios and 95% confidence intervals under an additive model (orange) and under a non-additive model for heterozygote KOs (blue) and homozygote KOs (green)