Table 1.
MLL-AF6 specific target genes
| Gene | Description | Fold change (log2) |
p value (-log10) |
|---|---|---|---|
| SHARP1 | Basic helix-loop-helix family, member e41 | 4.65 | 13.3 |
| P2RY1 | Purinergic receptor P2Y1 | 2.35 | 8.00 |
| SSPN | Sarcospan | 0.81 | 5.65 |
| FAM169A | Family with sequence similarity 169, member A | 1.71 | 5.21 |
| TRPS1 | Trichorhinophalangeal syndrome 1 | 1.89 | 5.02 |
| MMRN1 | Multimerin 1 | 2.82 | 3.43 |
| SKIDA1 | SKI/DACH domain containing 1 | 1.59 | 2.13 |
| HOXA7 | Homeobox A7 | 0.91 | 1.89 |
| SLC35D1 | Solute carrier family 35, member D1 | 0.58 | 1.39 |
A list of nine MLL-AF6 target genes presenting higher expression in MLL-AF6 AML than all the other subtypes of MLLr-AMLs