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. 2018 Apr 24;8:6439. doi: 10.1038/s41598-018-24615-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Variations of peak pressure, mean pressure and static compliance during the two hours of ventilation. H0: On connection of the ventilator, H0’: after recruitment maneuver, H1: after one hour of ventilation, H2: after 2 hours of ventilation. a, b and c denote a p value (Mann-Withney pairwise comparisons after Kruskal-Wallis test) <0.05 for the following pairwise comparisons: for VC vs OV_Tiw, VC vs OV_Taw and OV_Taw vs OV_Tiw, respectively. *Denotes p value (Mann-Withney pairwise comparison) <0.05 between H2 and H0’ in each group (n = 19–25 per group).