Table 1.
Upper-layer enriched astrocytic genes
| Gene symbol | RPKM | Fold change (upper/deep) | |||
|---|---|---|---|---|---|
| Upper | Deep | P value | Known functions in astrocytes (Refs) | ||
| Chrdl1 | 89.5 | 20.1 | 4.5 | 0.0038 | |
| Lef1 | 19.4 | 4.6 | 4.3 | 0.0074 | |
| Fmo1 | 32.5 | 12.2 | 2.7 | 0.0064 | |
| Ccdc80 | 24.1 | 17.3 | 1.4 | 0.019 | |
| Dio2 | 39.7 | 28.9 | 1.4 | 0.0091 | Regulation of fatty acid oxidation level ([34]) |
| Slc1a3 | 2538.5 | 1893.0 | 1.3 | 0.0056 | Regulation of synaptic activity ([39]) |
| Slc15a2 | 137.8 | 103.4 | 1.3 | 0.0097 | Regulation of peptide transport ([35]) |
| Fgfr3 | 302.3 | 227.0 | 1.3 | 0.0087 | Negative regulator of Gfap expression ([40]) |
| Cyp4f15 | 271.0 | 205.8 | 1.3 | 0.028 | |
| Mertk | 227.9 | 178.1 | 1.3 | 0.024 | Regulation of synapse elimination ([36]) |
| Vcam1 | 193.9 | 156.4 | 1.2 | 0.032 | |
| Gja1 | 2230.3 | 1847.3 | 1.2 | 0.027 | Regulation of cell survival ([37]) |