. 2018 Apr 25;9(4):147. doi: 10.1038/s41424-018-0017-4

Table 2.

Clinical characteristics and gene expression levels of atopic and non-atopic EoE patients

	Atopic vs. non-atopic	p
Time of evolution (months)	60.6 (45.1) vs. 28 (18.3)	0.250^a
Symptom score	9 (5.9) vs. 6 (2)	0.723^a
Symptoms
Dysphagia	57.1% vs. 100%	0.475^b
Food impaction	57.1% vs. 100%	0.475^b
Abdominal pain	42.9% vs. 0%	0.475^b
Heartburn	0% vs. 33.3%	0.300^b
Vomiting	14.3% vs. 0%	>0.999^b
Weight loss	14.3% vs. 0%	>0.999^b
Endoscopy findings
Reduced caliber	14.3% vs. 33.3%	>0.999^b
Normal mucosa	14.3% vs. 0%	>0.999^b
Longitudinal furrows	57.1% vs. 100%	0.475^b
Rings	71.4% vs. 66.7%	>0.999^b
Crêpe-paper appearance	28.6% vs. 33.3%	>0.999^b
White plaques	42.9% vs. 66.7%	>0.999^b
Peak eosinophil count	55 (30.4) vs. 61 (34.8)	0.908^a
TLR1 gene expression	2.2 (2.3) vs. 1.5 (2.4)	0.569^a
TLR2 gene expression	41.3 (62.9) vs. 44.2 (34.5)	0.909^a
TLR3 gene expression	10.5 (9.5) vs. 3.2 (4.4)	0.087^a
TLR4 gene expression	3.6 (9.3) vs. 3.1 (2.7)	0.569^a
TLR6 gene expression	2.1 (4.6) vs. 2.9 (3.1)	0.909^a
TLR9 gene expression	1.9 (6.7) vs. 3.8 (2.7)	0.425^a
16S gene expression	0.75 (0.5) vs. 0.54 (0.8)	0.732^a
MUC1 gene expression	1.1 (1.7) vs. 0.3 (0.9)	0.360^a
MUC2 gene expression	NA	—
MUC4 gene expression	14.4 (22.1) vs. 20.3 (10.6)	0.732^a
MUC5B gene expression	0.32 (0.51) vs. 0.09 (0.03)	0.138^a
MyD88 gene expression	2 (0.4) vs. 2.3 (0.5)	0.425^a
NF-κB gene expression	2.9 (0.8) vs. 4 (0.8)	0.305^a
IL-1α gene expression	0.13 (0.17) vs. 0.13 (0.06)	0.909^a
IL-1β gene expression	3.3 (5.6) vs. 8.8 (4.3)	0.125^a
IL-6 gene expression	0.21 (0.14) vs. 1.3 (1.2)	0.138^a
IL-8 gene expression	103 .7 (196.6) vs. 179.39 (138.1)	0.425^a
IL-10 gene expression	6.7 (5.7) vs. 29.9 (14.8)	0.087^a
TNF-α gene expression	1.8 (2.2) vs. 1 (2.2)	0.909^a
PRF1 gene expression	10.4 (8.7) vs. 7.9 (5.7)	0.909^a
iNOS gene expression	0.041 (0.03) vs. 0.03 (0.02)	0.909^a
GZMA gene expression	2.3 (1.7) vs. 3 (4.3)	0.909^a
GZMB gene expression	17.3 (18.7) vs. 26.3 (13)	0.425^a
IL-15 gene expression	13.1 (11.8) vs. 15.7 (6.3)	0.305^a
MICA gene expression	1.2 (1.3) vs. 0.8 (1.6)	0.909^a
MICB gene expression	2.8 (2.4) vs. 2.5 (0.6)	0.305^a
KLRK1 gene expression	1.7 (1.2) vs. 4.6 (4.4)	0.210^a

^a Mann–Whitney U-test

^b Chi-square test