FIGURE 2.

Fitted dose–response curves of viability of HepG2 cells under treatment of AQ or AQ-QI (A) and DEAQ or DEAQ-QI (B). HepG2 cells were exposed to test compounds for 2.5 h. GSH depletion was performed by addition of BSO (500 μM) 24 h before the exposure. Cells were recovered overnight and cell viability was measured by resazurin reduction activity. Results are presented as percentage relative to vehicle controls in respective treatment groups. Each data point represents the mean ± SD (n = 3).