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Effects of 50 μM AQ-QI and 30 μM DEAQ-QI on intracellular concentrations of reduced GSH (rGSH) (A), GSSG (B), and on the ratio of reduced GSH to GSSG (C) in HepG2 cells without BSO pretreatment. Mock- and GSTP1-transfected cells were treated with 50 μM AQ-QI or 30 μM DEAQ-QI for 2.5 h, after which GSH and GSSG levels were quantified as described section “Materials and Methods.” Results are presented as mean ± SD (n = 3).
