Table 2.
Allele frequency for PsV and controls
| SNP | Allele | Number (Allele frequency %) | χ 2 | p | OR (95% CI) | |
|---|---|---|---|---|---|---|
| Control N = 383 |
Patient N = 305 |
|||||
| rs4845454 | C | 314 (40.99) | 283 (46.39) | 4.033 | 0.045 | 1.246 (1.005–1.544) |
| rs6701216 | T | 240 (31.33) | 257 (42.13) | 17.165 | < 0.001 | 1.596 (1.278–1.992) |
| rs1886734 | T | 320 (41.78) | 285 (46.72) | 3.372 | 0.066 | 1.222 (0.986–1.514) |
| rs4085613 | A | 329 (42.95) | 294 (48.20) | 3.772 | 0.052 | 1.236 (0.998–1.530) |
| rs12023196 | C | 255 (33.29) | 282 (46.23) | 23.894 | < 0.001 | 1.723 (1.384–2.144) |
| rs512208 | T | 220 (28.72) | 276 (45.25) | 40.266 | < 0.001 | 2.051 (1.640–2.564) |
| rs4112788 | T | 296 (38.64) | 295 (48.36) | 13.089 | < 0.001 | 1.487 (1.199–1.844) |
The difference of allele frequency of the other 3 SNPs between the PsV and the controls did not reach the Bonferroni correction level
OR odds ratio, CI confidence interval, P asymptotic p value for the epistatic effect between the patient and control