Fig. 2.

B cells from Gal-3 KO mice had increased expression of genes related to GC formation and costimulatory molecules. a Heat maps of the expression of selected genes related to the GC reaction determined in B cells from WT and Gal-3 KO mice (n = 2 for both strains). b Statistical analysis of the frequency of CD80⁺, CD86⁺, IL-21R⁺, CXCR4⁺, Ki-67⁺, and CD69⁺ B220⁺ B cells from the spleen of 8-week-old WT and Gal-3 KO mice (n = 6 for both strains). c Radar plots summarising the B cell phenotype observed in the spleen of Gal-3 KO and WT mice (n = 6 for both strains). Data are the mean ± s.e.m. *p < 0.05, **p < 0.005 (unpaired Student’s t-test). a Data are representative of two independent experiments. b, c Data are representative of three independent experiments