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. 2018 Apr 18;9:399. doi: 10.3389/fphys.2018.00399

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Copyright © 2018 Chen, Yuan, Qian, Qian, Zhu, Wu, Dan, Xiao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determination of soft-thresholding power in WGCNA. (A) Analysis of the scale-free fit index for various soft-thresholding powers (β). (B) Analysis of the mean connectivity for various soft-thresholding powers. (C) Histogram of connectivity distribution when β = 7. (D) Checking the scale free topology when β = 7. (E) Dendrogram of all differentially expressed genes clustered based on a dissimilarity measure (1-TOM).