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(A) Schematic representation of DOX/ICG@HBs for fluorescence imaging guided chemo/photothermal therapy of cancer. (B) In vivo fluorescence imaging and biodistribution of MDA-MB-231 tumor-bearing BALB/c nude mice after intravenous injection of free ICG and DOX/ICG@HBs. (C) In vivo chemo/photothermal therapy and biocompatibility of DOX/ICG@HBs on 4T1 tumor-bearing BALB/c mice upon the 808 nm laser irradiation (2 W/cm2, 10 min) (Lin et al., 2017a).
