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CEACAM6 is involved in the initial binding of AIEC. The CEACAM6 glycoprotein is produced and distributed in clusters (A) on the surface of viable cells and (B,C) on late apoptotic blebs or ACMV. (D) Structured illumination super-resolution microscopy of CEACAM6 clustering at the initial bacterial binding sites. (E,F) CEACAM6 forms clusters upon contact with the bacterial cells, or the FimH protein.
