Table 1.
Baseline demographic characteristics, protein levels, and laboratory test values of 31 healthy volunteers.
| Characteristic | Median (range) | ||
|---|---|---|---|
| 100 mg (N = 10) | 250 mg (N = 10) | 500 mg (N = 11) | |
| Baseline tT, ng/mL | 6.44 (4.04–9.5) | 5.93 (4.2–10.6) | 5.78 (2.31–9.48) |
| Baseline fT, ng/dL | 2.41 (1.58–4.17) | 2.38 (0.28–3.55) | 2.44 (1.08–3.09) |
| Age, years | 26.5 (22–32) | 25.5 (22–39) | 30 (21–39) |
| Weight, kg | 82.2 (61.7–115) | 88.8 (61.7–105) | 84.7 (60.7–115) |
| Blood urea nitrogen, mg/dL | 14.5 (10–17) | 15 (9–18) | 15 (8–19) |
| Serum creatinine, mg/dL | 1.05 (0.8–1.5) | 1.1 (1–1.2) | 1 (0.9–1.2) |
| Creatinine clearance, mL/min | 124 (89.6–179) | 123 (90.4–153) | 125 (84.3–166) |
| Albumin, g/dL | 4.55 (4.4–6.9) | 4.55 (4.3–5.1) | 4.6 (1.6–5) |
| Globulin, g/dL | 2.75 (2–3.1) | 2.9 (2.4–3.5) | 3 (2.8–3.2) |
| Thyroxine‐binding globulin, ug/mL | 19.5 (10–31) | 18.5 (11–26) | 21 (14–26) |
| Sex hormone‐binding globulin, nmol/L | 26 (17–46) | 24.5 (11–48) | 22 (13–47) |
| Alkaline phosphatase, IU/L | 63.5 (52–89) | 52 (41–97) | 67 (50–98) |
| Lactate dehydrogenase, IU/L | 157 (141–194) | 158 (121–196) | 143 (111–184) |
| AST, IU/L | 23 (17–32) | 20.5 (14–53) | 18 (12–34) |
| ALT, IU/L | 22 (16–52) | 27.5 (12–47) | 19 (10–40) |
| GGT, IU/L | 22 (10–54) | 20 (10–54) | 18 (10–58) |
| Total bilirubin, mg/dL | 7.25 (6.9–8.1) | 7.5 (6.8–8.4) | 7.6 (7.1–8) |
| Direct bilirubin, mg/dL | 0.2 (0.2–0.4) | 0.25 (0.1–0.4) | 0.3 (0.1–0.5) |
| Triglyceride, mg/dL | 110 (40–335) | 122 (43–532) | 123 (58–538) |
| Cholesterol, mg/dL | 199 (140–238) | 184 (139–224) | 198 (162–241) |
| HDL, mg/dL | 39 (27–70) | 39 (21–54) | 33 (22–47) |
| LDL, mg/dL | 125 (65–186) | 116 (79–162) | 136 (79–181) |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma‐glutamyl transferase; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; fT, free testosterone; tT, free testosterone.