Table 1.

Biochemical profile before and after denosumab therapy (mean ± SD).

Graft	Before therapy			After therapy			p
	Creatinine (μmol/L)	s-Ca (mmol/L)	PTH (pmol/L)	Creatinine (μmol/L)	s-Ca (mmol/L)	PTH (pmol/L)
Pancreas and kidney	197.1 ± 114.8	2.42 ± 0.1	10.1 ± 4.4	197.2 ± 116.3	2.4 ± 0.1	10.8 ± 7.3	NS
N = 15	N = 15	N = 15	N = 15	N = 15	N = 15	N = 15
Kidney	192.8 ± 90.3	2.4 ± 0.1	14.8 ± 8.9	208.3 ± 104.9	2.46 ± 0.1	14.2 ± 9.4	NS
N = 34	N = 34	N = 34	N = 34	N = 34	N = 34	N = 34
Liver	161.3 ± 30.9	2.4 ± 0.1	8.4 ± 4.1	158.2 ± 28.4	2.39 ± 0.1	8.06 ± 5.3	NS
N = 14	N = 14	N = 14	N = 14	N = 14	N = 14	N = 14
Total	177.9 ± 91.7	2.4 ± 0.1	12.2 ± 7.6	186.0 ± 101.7	2.43 ± 0.1	12.0 ± 8.4	NS
N = 63	N = 63	N = 63	N = 63	N = 63	N = 63	N = 63