Table 1. Study characteristics.
| First author | Year | Setting | Multi center | Control treatment | N treatment group | N control group | Prevention or treatment? |
|---|---|---|---|---|---|---|---|
| Ad N [35] | 2002 | Cardiac surgery | No | Infusion furosemide | 39 | 36 | Prevention |
| Allen LA [36] | 2010 | Acute decompensated heart failure | No | Infusion furosemide | 21 | 20 | Prevention |
| Bayat F [37] | 2015 | Cardiac surgery | No | Standard care | 42 | 42 | Prevention |
| Barbanti M [38] | 2015 | Contrast-Induced AKI | No | Standard care | 56 | 56 | Prevention |
| Briguori C [39] | 2011 | Contrast-Induced AKI | Yes | Standard care | 146 | 146 | Prevention |
| Brown CB [40] | 1981 | AKI/ICU | No | Infusion furosemide | 28 | 28 | Treatment |
| Cantarovich F [15] | 1973 | AKI/ICU | No | Standard care | 39 | 19 | Treatment |
| Copeland JG [41] | 1983 | Cardiac surgery | No | Infusion furosemide | 9 | 9 | Prevention |
| Dussol B [42] | 2006 | Contrast-Induced AKI | No | 0.9% Saline | 79 | 77 | Prevention |
| Felker BM [43] | 2011 | Acute decompensated heart failure | No | Infusion furosemide | 156 | 152 | Prevention |
| Gu CQ [44] | 2013 | Contrast-induced AKI | Yes | Standard care | 422 | 437 | Prevention |
| Karayannopoulos S [16] | 1974 | AKI/ICU | No | Standard care | 10 | 10 | Treatment |
| Kleinknecht D [17] | 1976 | AKI/ICU | No | Placebo | 33 | 33 | Treatment |
| Kunt AT [45] | 2009 | Cardiac surgery | No | Infusion furosemide | 50 | 50 | Treatment |
| Llorens P [46] | 2014 | Acute decompensated heart failure | No | Infusion furosemide | 73 | 36 | Prevention |
| Marenzi G [47] | 2012 | Contrast-Induced AKI | Yes | Standard care | 87 | 83 | Prevention |
| Mojtahedzadeh M [48] | 2004 | AKI/ICU | No | Infusion furosemide | 11 | 11 | Prevention |
| Ostermann M [49] | 2007 | AKI/ICU | No | Infusion furosemide | 26 | 30 | Prevention |
| Palazzuoli A [50] | 2014 | Acute decompensated heart failure | No | Infusion furosemide | 39 | 43 | Prevention |
| Schuller D [51] | 1997 | AKI/ICU | No | Infusion furosemide | 19 | 14 | Treatment |
| Shah RA [52] | 2014 | Acute decompensated heart failure | No | Infusion furosemide | 30 | 60 | Treatment |
| Shilliday IR [53] | 1997 | AKI/ICU | No | Placebo | 32 | 30 | Treatment |
| Solomon R [22] | 1994 | Contrast-Induced AKI | No | Saline (± mannitol) | 25 | 53 | Prevention |
| Thomson MR [54] | 2010 | Acute decompensated heart failure | No | Infusion furosemide | 30 | 26 | Treatment |
| Usmiani T [55] | 2016 | Contrast-Induced AKI | No | Standard care | 57 | 63 | Prevention |
| Vargas Hein O [56] | 2005 | Cardiac surgery | No | Torsemide | 14 | 15 | Treatment |
| Yayla Ç [57] | 2015 | Acute decompensated heart failure | No | Infusion furosemide | 14 | 15 | Prevention |