Table 2.
IC50 or percentage of inhibition of 1o against a panel of methyltransferases.
| MT | IC50 (µM) | % inhibition at 100 µM |
|---|---|---|
| EZH1 complex | 138.5 | 43 |
| DOT1L | 6 | |
| G9a | 7 | |
| MLL1 complex | 7 | |
| SET7/9 | 0.8 | |
| PRMT1 | 8 | |
| DNMT1 | 0 |
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