Figure 5.

Matrix remodeling associated 7 (MXRA7) deficiency inhibits and MXRA7 overexpression promotes the expression of pro-inflammatory cytokines. (A,B) Serum was collected from different groups of mice 24 h after 1 ml/kg CCl₄ injection. Serum IFNγ, IL-6, TNF, MCP-1, IL-12p70, and IL-10 were determined using cytometric bead array mouse inflammation kit. (C,D) Livers were isolated from different groups of mice 24 h after 1 ml/kg CCl₄ injection. Expression of IFNγ, IL-6, TNF, MCP-1, and IL-1β mRNAs in livers was detected by reverse transcription-quantitative real-time PCR. Data are presented as the summary of three experiments. *p < 0.05.