FIG 1.

iut gene cluster organization. (A) Organization of the iut gene cluster in C. diphtheriae. The red box denotes the predicted DtxR binding motif within the iutA promoter region. Arrows indicate the promoters identified here. (B) dip0168-iutA intergenic region with notable elements, including the DtxR binding site, putative Zur binding site, transcription initiation site (+1), and promoter elements (−10 and −35). The +1 site was identified through 5′ RACE and DNA sequencing. The start codons for Dip0168 and IutA are in bold.