Table 1.
Characteristics when eGFR was first <35 mL/min/1.73m2 among CRIC and AASK participants who eventually required renal replacement therapy (hemodialysis or peritoneal dialysis).
| Characteristics during CKD | CRIC (N=770) | AASK (N=333) |
|---|---|---|
|
| ||
| Mean age (yrs) | 57.2 ± 11.0 | 51.7 ± 11.3 |
|
| ||
| Men | 455 (59.1) | 199 (59.8) |
|
| ||
| Black | 418 (54.3) | 333 (100%) |
|
| ||
| Annual household income | ||
| lowa | 337 (43.8) | 165 (49.6) |
| mediumb | 179 (23.2) | 117 (35.1) |
| high c | 135 (17.5) | 51 (15.3) |
| Declined to answer | 119 (15.5) | -- |
|
| ||
| Positive smoking history** | 449 (58.3%) | 179 (53.8%) |
|
| ||
| Diabetes | 523 (67.9%) | 17 (5.1%)* |
|
| ||
| Hypertension | 745 (96.8%) | 333 (100%) |
|
| ||
| Prevalent CVD | 340 (44.2%)1 | 168 (50.5%) 2 |
|
| ||
| Mean serum albumin (g/dL) | 3.7 ± 0.53 | 4.1 ± 0.44 |
|
| ||
| Cancer | 51 (6.6%) | 9 (2.6%) |
|
| ||
| Systolic BP (mm Hg) | 139.4 ± 24.13 | 147.0 ± 24.0 |
|
| ||
| Diastolic BP (mm Hg) | 72.9 ± 13.93 | 91.5 ± 16.3 |
|
| ||
| Median hemoglobin A1C (%) | 6.9 [5.9–8.1] | NA |
|
| ||
| COPD | 28 (3.7%)3 | NA |
|
| ||
| Fat free mass, kg | 63.4 ± 16.23 | NA |
Continuous variables given as mean ± SD or median [interquartile range]; categorical variables as count (percentage).
Defined as MI, stroke, CHF, or PVD based on self-report.
Heart disease was determined at baseline based on a combination of self-report, chart review, or baseline electrocardiogram reading
Missing serum albumin in n=5; missing BP in n=2; missing COPD in n=13; missing hemoglobin A1C in n=84; missing FFM in n=123 in CRIC
Missing serum albumin in n=14
at baseline enrollment
for CRIC, smoked > 100 cigarettes over lifetime; for AASK, current or past smoker determined at time of baseline enrollment
≤$20,000 for CRIC; <$15,000 (determined at baseline enrollment) for AASK
$20,001–$50,000 for CRIC; $15,000–39,999 (determined at baseline enrollment) for AASK
≥$50,001 for CRIC; >$40,000 (determined at baseline enrollment) for AASK
CRIC Chronic Renal Insufficiency Cohort; AASK African American Study of Kidney Disease and Hypertension; BP blood pressure; CKD chronic kidney disease; COPD chronic obstructive pulmonary disease; NA, not available