Figure 1. TC B cells expand Th17 T cells significantly more than B6 B cells in vitro.

Phenotypes of bm12 CD4⁺ T cells cultured in polarizing conditions in the presence of B6 or TC pBa1and sB2 cells for 5 d. A. Th17 polarization: representative FACS plots of CD4⁺-gated cells stained with IL-17A and Foxp3, and frequency of IL-17A⁺ CD4⁺ T cells. B. Treg polarization: Frequency of Foxp3⁺ CD4⁺ T cells. C. Th1 polarization: frequency of IFN-γ⁺ CD4⁺ T cells. Data represents n = 5–10 mice, expressed as means ± SEM. ** P < 0.01, *** P < 0.001.