. 2018 Feb 14;114(5):645–655. doi: 10.1093/cvr/cvy044

Table 3.

Commercially available nuclear receptor drugs

Nuclear receptor	Disease	Drug generic name (marketed drug)
GR	Metabolic and immunological Disorders	Dexamethasone (Dexasone), Prednisolone (Orapred)⁹⁴^,⁹⁵
ER	Breast cancer, obesity	Tamoxifen (Nolvadex), Raloxifene (Evista)⁹⁶^,⁹⁷
PPARα	Dyslipidaemia, atherosclerosis	Fenofibrate (Tricor)⁹⁸
PPARγ	Diabetes, obesity	Pioglitazone (Actos), Rosiglitazone (Avandia)⁹⁹^,¹⁰⁰
RAR	Leukaemia, acne	13-cis-retinoic acid (Isotretinoin)¹⁰¹
RXR	Leukaemia, Kaposi sarcoma, eczema	9-cis-retinoic acid (Alitretinoin), Bexarotene (Targretin)^102–104
VDR	Osteoporosis, calcium homeostasis	Calcitriol (Calcijex), Paricalcitol (Zemplar)¹⁰⁵^,¹⁰⁶