Table 2. Ranking of selected infectious diseases according to annual DALYs per 100,000 population, EU/EEA countries, 2009–2013.
| Infectious disease | Median (95% uncertainty interval)a | % of total DALYs | |||||
|---|---|---|---|---|---|---|---|
| Incidence per 100,000 population | Deaths per 100,000 population | DALYs per case | YLD per 100,000 population | YLL per 100,000 population | DALY per 100,000 population | ||
| Influenza | 5,887 (5,544–6,223) | 5.89 (5.54–6.22) | 0.01 | 5.42 (4.73–6.16) | 76.3 (71.9–80.7) | 81.8 (76.9–86.5) | 29.8 |
| Tuberculosis | 14.9 (14.7–15.2) | 1.10 (1.08–1.12) | 3.58 (3.55–3.62) | 9.20 (8.98–9.43) | 44.3 (43.5–45.1) | 53.5 (52.5–54.4) | 19.5 |
| Human immunodeficiency virus infection | 7.99 (7.44–8.55) | 0.15 (0.13–0.16) | 6.03 (5.86–6.20) | 43.1 (39.7–46.4) | 5.13 (4.53–5.64) | 48.2 (44.5–51.9) | 17.5 |
| Invasive pneumococcal disease | 11.0 (10.7–11.2) | 1.18 (1.15–1.21) | 2.74 (2.71–2.77) | 2.49 (2.25–2.73) | 27.6 (26.9–28.2) | 30.1 (29.3–30.8) | 10.9 |
| Legionnaires’ disease | 3.40 (2.77–4.01) | 0.37 (0.30–0.45) | 3.04 (2.73–3.36) | 0.02 (0.02–0.03) | 10.3 (8.21–12.4) | 10.3 (8.23–12.4) | 3.75 |
| Campylobacteriosis | 654 (599–707) | 0.18 (0.13–0.23) | 0.01 | 3.25 (2.73–3.87) | 5.03 (3.59–6.58) | 8.28 (6.68–10.0) | 3.01 |
| Hepatitis B | 2.84 (2.29–3.40) | 0.15 (0.09–0.21) | 2.79 (1.46–4.45) | 0.49 (0.30–0.72) | 7.37 (3.85–11.7) | 7.86 (4.19–12.2) | 2.86 |
| Invasive Haemophilus influenzae disease | 1.52 (1.51–1.53) | 0.17 | 3.43 (3.39–3.47) | 0.28 (0.24–0.31) | 4.94 (4.88–5.00) | 5.22 (5.15–5.29) | 1.90 |
| Invasive meningococcal disease | 0.85 (0.83–0.86) | 0.07 | 5.64 (5.59–5.70) | 0.39 (0.35–0.44) | 4.39 (4.31–4.48) | 4.78 (4.68–4.88) | 1.74 |
| Chlamydia infection | 186 (124–259) | < 0.01 | 0.02 (0.01–0.05) | 4.62 (2.16–9.0) | Negligible | 4.63 (2.16–9.03) | 1.68 |
| Salmonellosis | 211 (208–214) | 0.16 (0.15–0.17) | 0.02 | 0.86 (0.74–1.01) | 3.11 (2.85–3.36) | 3.97 (3.68–4.25) | 1.44 |
| Pertussis | 263 (211–317) | 0.02 | 0.01 | 2.04 (1.59–2.56) | 1.28 (1.14–1.45) | 3.33 (2.78–3.94) | 1.21 |
| Shiga toxin/verocytotoxin-producing Escherichia coli (STEC/VTEC) infection | 48.1 (36.2–59.4) | 0.05 (0.04–0.07) | 0.05 (0.05–0.06) | 0.62 (0.49–0.76) | 1.98 (1.56–2.44) | 2.59 (2.05–3.21) | 0.94 |
| Listeriosis | 0.56 (0.52–0.59) | 0.08 (0.08–0.09) | 3.65 (3.52–3.79) | 0.20 (0.15–0.25) | 1.84 (1.74–1.94) | 2.04 (1.92–2.16) | 0.74 |
| Rubella | 51.6 | < 0.01 | 0.02 (0.01–0.02) | 0.55 (0.39–0.74) | 0.37 (0.29–0.45) | 0.92 (0.71–1.15) | 0.33 |
| Gonorrhoea | 34.2 (24.4–44.2) | < 0.01 | 0.02 (0.01–0.04) | 0.77 (0.49–1.24) | 0.01 (0.01–0.02) | 0.78 (0.50–1.26) | 0.28 |
| Hepatitis A | 10.0 (9.67–10.4) | 0.02 | 0.07 (0.06–0.08) | 0.14 (0.11–0.17) | 0.58 (0.51–0.66) | 0.72 (0.64–0.80) | 0.26 |
| Tick-borne encephalitis | 3.00 (2.87–3.13) | < 0.01 | 0.23 (0.22–0.24) | 0.46 (0.43–0.49) | 0.23 (0.22–0.25) | 0.69 (0.65–0.74) | 0.25 |
| Shigellosis | 27.0 (23.4–30.7) | 0.01 (0.01–0.02) | 0.03 (0.02–0.03) | 0.09 (0.08–0.11) | 0.59 (0.41–0.82) | 0.68 (0.49–0.93) | 0.25 |
| Measles | 7.46 | < 0.01 | 0.08 (0.07–0.08) | 0.14 (0.11–0.17) | 0.42 (0.38–0.46) | 0.56 (0.51–0.61) | 0.20 |
| Congenital toxoplasmosis | 0.19 (0.11–0.28) | < 0.01 | 2.42 (1.92–3.05) | 0.34 (0.17–0.56) | 0.12 (0.06–0.19) | 0.46 (0.24–0.73) | 0.17 |
| Giardiasis | 88.9 (75.0–104) | < 0.01 | < 0.01 | 0.36 (0.30–0.43) | 0.05 (0.04–0.06) | 0.41 (0.34–0.48) | 0.15 |
| Q fever | 1.58 | < 0.01 | 0.20 (0.16–0.23) | < 0.01 | 0.31 (0.25–0.36) | 0.31 (0.26–0.37) | 0.11 |
| Tetanus | 0.06 (0.05–0.07) | < 0.01 | 2.02 (1.91–2.15) | < 0.01 | 0.12 (0.11–0.13) | 0.12 (0.11–0.13) | 0.04 |
| Mumps | 24.2 (22.6–25.8) | < 0.01 | < 0.01 | 0.07 (0.06–0.07) | 0.02 | 0.09 (0.08–0.10) | 0.03 |
| Cryptosporidiosis | 34.7 (32.3–37.1) | < 0.01 | < 0.01 | 0.03 (0.02–0.03) | 0.06 (0.05–0.06) | 0.08 (0.08–0.09) | 0.03 |
| Syphilis | 2.04 (1.68–2.38) | < 0.01 | 0.04 (0.04–0.05) | 0.04 (0.03–0.04) | 0.05 | 0.08 (0.08–0.09) | 0.03 |
| variant Creutzfeldt–Jakob disease | < 0.01 | < 0.01 | 48.6 (48.4–48.8) | < 0.01 | 0.04 | 0.04 | 0.01 |
| Diphtheria | 0.02 | < 0.01 | 1.16 | < 0.01 | 0.02 | 0.02 | 0.01 |
| Rabies | < 0.01 | < 0.01 | 52.1 | < 0.01 | 0.01 | 0.01 | < 0.01 |
| Total | 7,577 (6,445–8,141) | 9.67 (8.47–10.3) | NA | 75.9 (66.0–87.0) | 196 (181–213) | 273 (249–299) | 100 |
DALYs: disability-adjusted life years; EU/EEA: European Union/European Economic Area; YLD: years lived with disability: YLL: years of life lost; NA: not applicable.
a Median and 95% uncertainty interval as estimated from the Burden of Communicable Diseases in Europe (BCoDE) toolkit (10,000 Monte Carlo simulations).
Values < 0.01 are not specified. Uncertainties that deviate less than 0.01 from the median are not specified.