Table 4.
Multivariable associations of patient and treatment characteristics with OS and LSS among AYA with ALL, ages 15-24 y, 2004-2014, California
| OS | LSS | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Sex | .26 | .53 | ||
| Female | 0.86 (0.66-1.12) | 0.92 (0.70-1.21) | ||
| Male | Ref. | Ref. | ||
| Age at diagnosis, y | .51 | .94 | ||
| 15-18 | 0.89 (0.64-1.25) | 1.01 (0.71-1.44) | ||
| 19-24 | Ref. | Ref. | ||
| Race/ethnicity | <.001 | <.001 | ||
| Asian/PI | 1.30 (0.72-2.37) | 1.45 (0.78-2.76) | ||
| Hispanic | 2.30 (1.59-3.31) | 2.48 (1.66-3.94) | ||
| NH African American | 3.10 (1.63-5.88) | 3.13 (1.56-6.32) | ||
| Other/ unknown | 0.86 (0.12-6.28) | 1.09 (0.15-7.99) | ||
| NH white | Ref. | Ref. | ||
| Treatment setting | .001 | .001 | ||
| Pediatric | 0.51 (0.35-0.74) | 0.51 (0.34-0.76) | ||
| Adult | Ref. | Ref. | ||
| Induction facility is COG center or NCI CC | .07 | .029 | ||
| Yes | 0.77 (0.58-1.02) | 0.72 (0.53-0.97) | ||
| No | Ref. | Ref. | ||
Final model includes age, sex, and all variables significant at the P < .10 level.