Table 5.
Multivariable associations of patient and treatment characteristics with OS and LSS among AYA with ALL treated in an adult setting, ages 15-39 y, 2009-2014, California
| OS | LSS | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Sex | .27 | .59 | ||
| Female | 0.82 (0.58-1.16) | 0.90 (0.62-1.31) | ||
| Male | Ref. | Ref. | ||
| Race/ethnicity | .60 | .04 | ||
| Asian/PI | 1.39 (0.73-2.62) | 1.73 (0.85-3.51) | ||
| Hispanic | 1.82 (1.22-2.74) | 2.10 (1.31-3.35) | ||
| NH African American | 2.04 (0.78-5.36) | 2.19 (0.74-6.51) | ||
| Other/ unknown | 2.02 (0.48-8.56) | 2.80 (0.64-12.17) | ||
| NH white | Ref. | Ref. | ||
| Front-line ALL regimen | .83 | .21 | ||
| Pediatric | 1.05 (0.70-1.57) | 1.33 (0.85-2.08) | ||
| Adult | Ref. | Ref. | ||
| Induction facility is COG center or NCI CC | 0.28 | 0.10 | ||
| Yes | 0.81 (0.56-1.19) | 0.70 (0.46-1.07) | ||
| No | Ref. | Ref. | ||
Final model is stratified on age and includes sex, type of induction, NCI/COG CC status, and all variables significant at the P < .10 level.