Table 2.
Outcomes | 55-64 years (N = 1183) | ≥65 years (N = 446) | P | ||
---|---|---|---|---|---|
n | Probability, % (95% CI) | n | Probability, % (95% CI) | ||
Acute GVHD (II-IV), 180 d | 1108 | 38 (35-41) | 425 | 35 (31-40) | 0.39 |
Acute GVHD (III-IV), 180 d | 1108 | 15 (13-17) | 426 | 17 (14-21) | 0.21 |
Chronic GVHD, y | 1145 | 438 | |||
1 | 40 (37-43) | 35 (31-40) | 0.06 | ||
2 | 48 (45-51) | 45 (40-49) | 0.25 | ||
NRM | 1183 | 446 | |||
100 d | 7 (5-8) | 7 (5-10) | 0.69 | ||
1 y | 15 (13-17) | 18 (15-22) | 0.14 | ||
4 y | 24 (21-27) | 30 (25-35) | 0.03 | ||
Relapse/progression, y | 1183 | 446 | |||
1 | 30 (27-32) | 29 (24-33) | 0.70 | ||
4 | 41 (38-44) | 42 (37-47) | 0.82 | ||
PFS, y | 1183 | 446 | |||
1 | 55 (52-58) | 53 (49-59) | 0.51 | ||
4 | 37 (34-40) | 31 (26-35) | 0.03 | ||
OS, y | 1183 | 446 | |||
1 | 69 (67-72) | 67 (62-71) | 0.31 | ||
4 | 51 (48-54) | 46 (41-51) | 0.07 |