. 2018 Feb 20;9(11):3041–3049. doi: 10.1039/c7sc05122k

Table 3. N-substituents on the benzylamine ^a .


Compound	R	Inhibition of the kinase activity @ 500 μM (%)	PDB
1	H	21	5CSH
16		54	n.a.
17		42	n.a.
18		40	6EII
19		52	5OT6
20		50	5OUE
21		n.d.	5OUM
22		98 (IC₅₀ 58)	5OUU

^an.d. = interference with the assay by the test compound.

Table 3. N-substituents on the benzylamine a .