Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2019 May 1.

Published in final edited form as: J Pharm Sci. 2017 Dec 21;107(5):1269–1281. doi: 10.1016/j.xphs.2017.12.015

High-c₂ predictions of R^ex/K and S_q=0 from low-c₂ parameters with the HEXA model shown in Fig. 4, for pH 5 (panels A and C) and pH 6.5 (panels B and D) and for buffer-only (black squares), 5% w/w sucrose (red triangles) and 100 mM NaCl (gray circles). The symbols represent the experimental data from insets in Fig. 3 while shaded areas represent the model predictions. The blue dashed line represents the steric-only behavior.

High-c₂ predictions of R^ex/K and S_q=0 from low-c₂ parameters with the HEXA model shown in Fig. 4, for pH 5 (panels A and C) and pH 6.5 (panels B and D) and for buffer-only (black squares), 5% w/w sucrose (red triangles) and 100 mM NaCl (gray circles). The symbols represent the experimental data from insets in Fig. 3 while shaded areas represent the model predictions. The blue dashed line represents the steric-only behavior.