Table 1.
Norepinephrine turnover (ng NE/g tissue/hr) in high-capacity runners (HCR) and low-capacity runners (LCR) 4 hrs after intra-ventromedial hypothalamic microinjection of either the mixed melanocortin receptor agonist MTII or vehicle. Mean±SEM
Tissue | HCR | LCR | |||
---|---|---|---|---|---|
vehicle | MTII* | vehicle | MTII* | ||
White adipose tissue | Mesenteric†** | 18.88** ± 2.30 | 38.73** ± 4.72 | 8.39 ± 0.71 | 15.24 ± 1.30 |
Retroperitoneal | 8.04 ± 0.70 | 13.99 ± 1.23 | 6.32 ± 0.87 | 11.34 ± 1.56 | |
Epididymal†** | 5.22** ± 0.60 | 7.58** ± 0.87 | 2.05 ± 0.11 | 5.56 ± 0.31 | |
Gluteal†** | 4.92 ± 0.30 | 7.95** ± 0.49 | 4.19 ± 0.37 | 4.52 ± 0.40 | |
Inguinal†** | 2.29 ± 0.19 | 3.88** ± 0.32 | 1.90 ± 0.17 | 2.43 ± 0.22 | |
Brown adipose tissue†** | 27.45** ± 1.54 | 62.50** ± 3.51 | 18.36 ± 1.06 | 30.91 ± 1.78 | |
Liver† | 0.85 ± 0.10 | 2.11** ± 0.26 | 0.66 ± 0.06 | 1.17 ± 0.10 |
HCR, high-capacity runners; LCR, low-capacity runners (N=7/HCR, 8/LCR)
MTII>vehicle, within line (HCR/LCR) when interaction was significant; all tissues showed main effect of MTII; p<0.05
HCR≠LCR within treatment indicated; main effect of line (HCR/LCR) indicated on tissue; p<0.05
Significant interaction between treatment (vehicle/MTII) and line (HCR/LCR); p<0.05