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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Cytokine. 2018 Jul;107:130–136. doi: 10.1016/j.cyto.2018.01.016

Figure 1.

Figure 1

Inactivation of CD80/CD86 improves survival of mice in a model of S. aureus pneumonia. A) WT and Cd80Cd86−/− mice were infected with 1 × 108 cfu of S. aureus USA300 and survival was followed for seven days. Data are from three independent experiments. n=WT-14 and Cd80Cd86−/−-8. B) C57BL/6J WT and Cd80Cd86−/− mice were infected with 4 × 107 cfu of S. aureus intranasally for 24 h. Bacterial counts were assessed in BALF and lung homogenate, and external body temperatures were measured before euthanasia. Data are from four independent experiments. Each point represents a mouse. Lines display median. **P<0.01.