Figure 3.
Cd80Cd86−/− mice exhibit a decreased inflammatory response to S. aureus in a model of acute pneumonia. C57BL/6J WT and Cd80Cd86−/− mice were infected with 4 × 107 cfu of S. aureus intranasally for 24 h. Cytokines were quantified from BALF. Data is from four independent experiments. Graphs display means with standard error. n=3-PBS/uninfected and 14 for infected animals. ****P<0.0001, ***P<0.001, **P<0.01 and *P<0.05 compared to WT infected.