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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Immunol. 2018 Mar 30;200(9):3128–3141. doi: 10.4049/jimmunol.1701573

Figure 1. Increased expression of Lcn2 in the retina and brain after light exposure.

Figure 1

Abca4−/−Rdh8−/− mice (1-month-old) were exposed to light at 10,000 lux for 30 min. A. Various tissues including the eye, liver, heart, brain, spleen, lung and kidney were collected 24 h after light exposure. RNA levels are presented as fold change over non-light exposed control tissues. B. Immunoblot of LCN2 protein in light exposed 1-month-old Abca4−/−Rdh8−/− mice 1, 3, and 7 days after light exposure. C. Quantitative analyses of the immunoblot after normalization to β-actin are presented. D. Serum was collected from 1-month-old Abca4−/−Rdh8−/− mice at different time points after light exposure. E. Immunohistochemistry of LCN2 protein in the retinal sections of 1-month-old Abca4−/−Rdh8−/− mice 24 h after light exposure. Scale bar: 50 μm. RPE, retinal pigmented epithelium; ONL, outer nuclear layer; INL, inner nuclear layer; GCL ganglion cell layer. Error bars indicate S.D. of the means, n=3, *p < 0.05.