A. RNA was extracted from human RPE cells differentiated from induced pluripotent stem cells (hiPS-RPE), ARPE19 (a human RPE derived cell line) and human primary RPE cells. Expression of SLC22A17 was examined. Error bars indicate S.D. of the means, n=6. B.
Abca4−/−Rdh8−/− mice (1-month-old) were exposed to light at 10,000 lux for 30 min. RNA was extracted from RPE cells at different times points after light exposure. Expression levels of 24p3r are presented as fold induction over non-light exposed control. Error bars indicate S.D. of the means, n=3, *p < 0.05.