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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Immunol. 2018 Mar 30;200(9):3128–3141. doi: 10.4049/jimmunol.1701573

Figure 3. Deficiency of Lcn2 resulted in severe light-induced retinal degeneration in Abca4−/−Rdh8−/− mice.

Figure 3

A. Representative retinal histology (upper panel) and SLO (lower panel) of 1-month-old Lcn2−/−Abca4−/−Rdh8−/− and Abca4−/−Rdh8−/− mice 7 days after light exposure at 10,000 lux for 30 min are shown. Scale bar: 20 μm. B. ONL thickness measurements of 1-month-old Lcn2−/−Abca4−/−Rdh8−/− and Abca4−/−Rdh8−/− mice 7 days after light exposure is presented. C. Numbers of autofluorescent (AF) spots detected by SLO in 1-month-old Lcn2−/−Abca4−/−Rdh8−/− and Abca4−/−Rdh8−/− mice 7 days after light exposure were counted. Error bars indicate S.D. of the means, n=3, *p < 0.05.