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. 2018 Feb 22;3(4):e92193. doi: 10.1172/jci.insight.92193

Figure 6. Conditional Vhl-null and –type 2B mutations induce gross vascular dysmorphogenesis and severe mislocalization of αSMA in P21 mouse retinas.

Figure 6

(A–D) Representative images of P21 mouse retinal vasculature stained with isolectin B4 (top row) and αSMA (middle row). An artery-vein pair is shown for UBC+/+Vhlfl/fl (A), UBC+/+Vhlfl/2B (B), UBCCreER/+Vhlfl/fl (C), and UBCCreER/+Vhlfl/2B (D) littermate retinas exposed to tamoxifen. Scale bars: 100 μm.