Table 1.
Baseline Subject Values (N=208)
| Characteristic | Median (25th–75th%) | Actual # of subjects |
|---|---|---|
| Demographic Characteristics | ||
| Gender (male), n (%) | 208 (100%) | 208 |
| Ethnicity (Hispanic), n (%) | 208 (100%) | 208 |
| Age (years) | 12.0 (11.0–14.0) | 208 |
| BMI (kg/m2) | 31.4 (27.8–35.5) | 207 |
| BMI Z-Score | 2.4 (2.1–2.6) | 208 |
| Waist/Hip Ratio | 1.00 (0.96–1.04) | 207 |
| Diabetes mellitus, n (%) | 4 (2) | 4 |
| Laboratory Measures | ||
| ALT (U/L) | 83 (61–138) | 208 |
| AST (U/L) | 51 (38–72) | 208 |
| Total cholesterol, mg/dL | 167 (142.5–187) | 207 |
| HDL cholesterol, mg/dL | 38 (32–43) | 207 |
| LDL cholesterol, mg/dL | 101 (83.3–118.8) | 206 |
| Triglycerides, mg/dL | 118 (82–157.5) | 207 |
| Serum glucose (mg/dl) | 86 (82–92) | 207 |
| Serum insulin(U/ml) | 26 (17–42) | 201 |
| HBA1c (%) | 5.3 (5.1–5.5) | 205 |
| Histologic characteristics | ||
| Steatosis, n (%) | NASH CRN Score | Number of Subjects (Percentage of total) |
| <5% | 0 | 8 (4) |
| 5%–33% | 1 | 52 (25) |
| 34%–66% | 2 | 60 (29) |
| >66% | 3 | 88 (42) |
| Lobular inflammation, n (%) | NASH CRN Score | |
| 0 | 0 | 0 (0) |
| <2 under 20x magnification | 1 | 113 (54) |
| 2–4 under 20x magnification | 2 | 81 (39) |
| >4 under 20_xmagnification | 3 | 14 (7) |
| Ballooning, n (%) | NASH CRN Score | |
| None | 0 | 123 (59) |
| Few | 1 | 54 (26) |
| Many | 2 | 31 (15) |
| NASH diagnosis, n (%) | ||
| No NASH | 48 (23) | |
| Borderline zone 3 pattern | 26 (13) | |
| Borderline zone 1 pattern | 84 (40) | |
| Yes, definite | 46 (22) | |
| Missing | 4 (2) |