Fig. 5.

GM-CSF modifies Aβ transporter levels in AD mice brain. (A) The expression of of LRP1 and RAGE in non-Tg and AD animal groups was determined by Western blot analysis. (B, C) Densitometric analysis of LRP1 (B) and RAGE (C) expression in GM-CSF-treated or untreated mice (n = 4 per group). Data are presented as mean intensity of expression ± SEM, and ^aap ≤ 0.01, ^bp≤0.05, ^bbp ≤ 0.01 and ^cp ≤ 0.05 compared to ^aanon-Tg/PBS, ^b,bbnon-Tg/GM-CSF, or ^cAD/PBS as determined by one-way ANOVA and Newman-Keuls post-hoc test.