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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Immunol. 2018 Apr 2;200(9):3244–3258. doi: 10.4049/jimmunol.1701733

Fig 4. Analysis of genes characteristic of Th1 differentiation and validation in PBMC.

Fig 4

(A) Log-transformed, normalized counts for select genes at 6h and 24h, mean ± SEM, statistical significance of differential expression (as compared to media at each timepoint) is reported as Benjamini-Hochberg adjusted p-value. (B) PBMC were stimulated with mTB tRNA, ssRNA or TLR2/1L and cytokine secretion measured at 24h. (n=20). Statistical significance of ligand-stimulated PBMC vs. media control calculated by one-way repeated measures ANOVA followed by Dunnett’s multiple comparisons test. *p<= 0.05, ** p<=0.01, *** p<=0.001