Riluzole blocks cocaine-induced decrease in GLT-1. Normalized GLT-1/Cxn expression. Expression levels are normalized to Saline–Vehicle. Representative western blots showed bands corresponding to GLT-1 and calnexin (Cxn, control loading protein) expression from Saline–Vehicle, Saline–4 mg/kg, Cocaine–Vehicle, and Cocaine–4 mg/kg groups. *P<0.05 compared with all other groups. The x axis indicates self-administration group, and legend indicates treatment group.