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. 2017 Dec 20;43(6):1297–1307. doi: 10.1038/npp.2017.281

Figure 2.

Figure 2

Variations in early life maternal care regulate generalization of fear-associated freezing following auditory fear conditioning. Fear-associated freezing following cued fear conditioning in response to a neutral stimulus (CS−) and the conditioned stimulus (CS+). Bar graphs denote mean+SEM of percent of time during each stimulus presentation period spent freezing. Offspring of high LG mothers froze significantly more than offspring of low LG mothers when presented with CS−, and only offspring of high LG mothers froze significantly more in response to CS− than to the background context. (offspring of high LG dams: n=12 rats; offspring of low LG dams: n=11 rats) *P<0.05.