. 2018 Jan 24;43(6):1247–1256. doi: 10.1038/npp.2017.298

Table 3. P-values and Effect Sizes for Interactions Between Medication and Permutations of DAT1 VNTR and Other DA-Related Polymorphisms.

	VS activation (n=81)		Bar lab drinks (n=94)
Genotype permutation	p	η_p²	p	η_p²
DAT1	0.026	0.063	0.032	0.050
DAT1+COMT	0.19	0.023	0.007	0.079
DAT1+DRD2	0.021	0.068	0.006	0.081
DAT1+DRD4	0.014	0.077	0.045	0.045
DAT1+COMT+DRD2	0.16	0.026	0.002	0.100
DAT1+COMT+DRD4	0.087	0.038	0.011	0.071
DAT1+DRD2+DRD4	0.01	0.084	0.011	0.072
DAT1+COMT+DRD2+DRD4	0.046	0.051	0.013	0.069

Statistics are for the interaction between medication (aripiprazole vs. placebo) and each permutation of genotypes (additive effect of number of DAT1 9R, COMT met, DRD2 T, and/or DRD4 long alleles) in a general linear model that also included baseline drinks per day and the main effects of medication and the genotype permutation. P-values for significant interactions (p<0.05) are bolded.