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. 2018 Mar 16;159(5):929–938. doi: 10.1097/j.pain.0000000000001209

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Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain.

This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Resting-state connectivity in (A) healthy controls (HCs), patients with chronic knee osteoarthritis (OA) and differences between these groups (FWE P < 0.05) of the (B) right anterior insula. (C) Mean (+SEM) z values of those clusters displaying a significant group difference are displayed on a bar graph to visualise the anticorrelations observed in patients with chronic knee OA. All slice images are displayed in radiological convention (right hemisphere is displayed on the left of the figure). PCC, posterior cingulate cortex.