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. 2018 Jan 29;10(3):370–379. doi: 10.1080/19420862.2018.1424610

Table 2.

Summary of neutralization activities of anti-rituximab mAbs.

IC50 (μg/ml) Binding CDC ADCC (FcγRIIIa activation)
ADA03 0.245 0.158 0.127
ADA05 0.356 0.167 0.102
ADA06 0.355 0.225 0.211
ADA08 0.294 0.166 0.138
ADA10 0.219 0.149 0.900
ADA12 0.249 0.167 0.137
ADA13 0.577 0.530 1.106
ADA19 0.287 0.172 0.678