Figure 1.
Scatterplot of log odds ratio (OR) of individual SNPs in their association with breast cancer risk in ROOT, WHI, AABC and BCAC. Blue circles represent genetic variants with the same direction between the two studies, whereas red squares represent SNPs exhibiting flip-flop.
Abbreviations: WHI – Women’s Health Initiative (African American); AABC – African-American Breast Cancer GWAS study; BCAC – Breast Cancer Association Consortium (European ancestry); ROOT – GWAS of Breast Cancer in the African Diaspora.